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Sildenafil does not enhance but rather attenuates vasorelaxant effects of antidiabetic agents
Type 2 diabetic men commonly experience erectile dysfunction for which phosphodiesterase-5 (PDE5) inhibitors like sildenafil (Viagra) are often recommended. By preventing degradation of cyclic guanosine monophosphate (cGMP) in vascular smooth muscle, these inhibitors also enhance arterial vasorelaxa...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Japan Society of Smooth Muscle Research
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137313/ https://www.ncbi.nlm.nih.gov/pubmed/26004378 http://dx.doi.org/10.1540/jsmr.51.22 |