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Orchidectomy enhances the expression of endothelin-1 and ET(B) receptors in rat portal vein

Functional studies have shown that orchidectomy increases the effects of phenylephrine on rat portal veins, but that it is completely prevented in the presence of both ET(A) and ET(B) receptor antagonists. Although it suggests the involvement of endothelin-1 (ET-1), the local production of this vaso...

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Detalles Bibliográficos
Autores principales: Rossignoli, Patrícia de S., De Labio, Roger W., Payão, Spencer L. M., Pereira, Oduvaldo C. M., Chies, Agnaldo B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japan Society of Smooth Muscle Research 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137319/
https://www.ncbi.nlm.nih.gov/pubmed/26081371
http://dx.doi.org/10.1540/jsmr.50.85