Evaluating the impact of single nucleotide variants on transcription factor binding

Diseases and phenotypes caused by disrupted transcription factor (TF) binding are being identified, but progress is hampered by our limited capacity to predict such functional alterations. Improving predictions may be dependent on expanding the set of bona fide TF binding alterations. Allele-specifi...

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Detalles Bibliográficos
Autores principales: Shi, Wenqiang, Fornes, Oriol, Mathelier, Anthony, Wasserman, Wyeth W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137422/
https://www.ncbi.nlm.nih.gov/pubmed/27492288
http://dx.doi.org/10.1093/nar/gkw691

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137422/
https://www.ncbi.nlm.nih.gov/pubmed/27492288
http://dx.doi.org/10.1093/nar/gkw691

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