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Incision of damaged DNA in the presence of an impaired Smc5/6 complex imperils genome stability
The Smc5/6 complex is implicated in homologous recombination-mediated DNA repair during DNA damage or replication stress. Here, we analysed genome-wide replication dynamics in a hypomorphic budding yeast mutant, smc6-P4. The overall replication dynamics in the smc6 mutant is similar to that in the w...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137426/ https://www.ncbi.nlm.nih.gov/pubmed/27536003 http://dx.doi.org/10.1093/nar/gkw720 |