Distinctive Klf4 mutants determine preference for DNA methylation status

Reprogramming of mammalian genome methylation is critically important but poorly understood. Klf4, a transcription factor directing reprogramming, contains a DNA binding domain with three consecutive C2H2 zinc fingers. Klf4 recognizes CpG or TpG within a specific sequence. Mouse Klf4 DNA binding dom...

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Detalles Bibliográficos
Autores principales: Hashimoto, Hideharu, Wang, Dongxue, Steves, Alyse N., Jin, Peng, Blumenthal, Robert M., Zhang, Xing, Cheng, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137437/
https://www.ncbi.nlm.nih.gov/pubmed/27596594
http://dx.doi.org/10.1093/nar/gkw774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137437/
https://www.ncbi.nlm.nih.gov/pubmed/27596594
http://dx.doi.org/10.1093/nar/gkw774

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