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Distinctive Klf4 mutants determine preference for DNA methylation status

Reprogramming of mammalian genome methylation is critically important but poorly understood. Klf4, a transcription factor directing reprogramming, contains a DNA binding domain with three consecutive C2H2 zinc fingers. Klf4 recognizes CpG or TpG within a specific sequence. Mouse Klf4 DNA binding dom...

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Detalles Bibliográficos
Autores principales:	Hashimoto, Hideharu, Wang, Dongxue, Steves, Alyse N., Jin, Peng, Blumenthal, Robert M., Zhang, Xing, Cheng, Xiaodong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137437/ https://www.ncbi.nlm.nih.gov/pubmed/27596594 http://dx.doi.org/10.1093/nar/gkw774

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