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Casposon integration shows strong target site preference and recapitulates protospacer integration by CRISPR-Cas systems
Casposons are a recently discovered group of large DNA transposons present in diverse bacterial and archaeal genomes. For integration into the host chromosome, casposons employ an endonuclease that is homologous to the Cas1 protein involved in protospacer integration by the CRISPR-Cas adaptive immun...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137440/ https://www.ncbi.nlm.nih.gov/pubmed/27655632 http://dx.doi.org/10.1093/nar/gkw821 |