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Casposon integration shows strong target site preference and recapitulates protospacer integration by CRISPR-Cas systems

Casposons are a recently discovered group of large DNA transposons present in diverse bacterial and archaeal genomes. For integration into the host chromosome, casposons employ an endonuclease that is homologous to the Cas1 protein involved in protospacer integration by the CRISPR-Cas adaptive immun...

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Detalles Bibliográficos
Autores principales:	Béguin, Pierre, Charpin, Nicole, Koonin, Eugene V., Forterre, Patrick, Krupovic, Mart
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137440/ https://www.ncbi.nlm.nih.gov/pubmed/27655632 http://dx.doi.org/10.1093/nar/gkw821

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