Differential cytokine sensitivities of STAT5-dependent enhancers rely on Stat5 autoregulation

Cytokines utilize the transcription factor STAT5 to control cell-specific genes at a larger scale than universal genes, with a mechanistic explanation yet to be supplied. Genome-wide studies have identified putative STAT5-based mammary-specific and universal enhancers, an opportunity to investigate...

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Detalles Bibliográficos
Autores principales: Willi, Michaela, Yoo, Kyung Hyun, Wang, Chaochen, Trajanoski, Zlatko, Hennighausen, Lothar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137441/
https://www.ncbi.nlm.nih.gov/pubmed/27694626
http://dx.doi.org/10.1093/nar/gkw844

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137441/
https://www.ncbi.nlm.nih.gov/pubmed/27694626
http://dx.doi.org/10.1093/nar/gkw844

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