Dynamic peptides of human TPP1 fulfill diverse functions in telomere maintenance

Telomeres are specialized nucleoprotein complexes that comprise the ends of linear chromosomes. Human telomeres end in a short, single-stranded DNA (ssDNA) overhang that is recognized and bound by two telomere proteins, POT1 and TPP1. Whereas POT1 binds directly to telomere ssDNA, its interaction wi...

Descripción completa

Detalles Bibliográficos
Autores principales: Rajavel, Malligarjunan, Orban, Tivadar, Xu, Mengyuan, Hernandez-Sanchez, Wilnelly, de la Fuente, Maria, Palczewski, Krzysztof, Taylor, Derek J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137443/
https://www.ncbi.nlm.nih.gov/pubmed/27655633
http://dx.doi.org/10.1093/nar/gkw846

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137443/
https://www.ncbi.nlm.nih.gov/pubmed/27655633
http://dx.doi.org/10.1093/nar/gkw846

Ejemplares similares