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Codon usage is less optimized in eukaryotic gene segments encoding intrinsically disordered regions than in those encoding structural domains

Codon usage tends to be optimized in highly expressed genes. A plausible explanation for this phenomenon is that translational accuracy is increased in highly expressed genes with infrequent use of rare codons. Besides structural domains (SDs), eukaryotic proteins generally have intrinsically disord...

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Detalles Bibliográficos
Autores principales: Homma, Keiichi, Noguchi, Tamotsu, Fukuchi, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137448/
https://www.ncbi.nlm.nih.gov/pubmed/27915289
http://dx.doi.org/10.1093/nar/gkw899