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Codon usage is less optimized in eukaryotic gene segments encoding intrinsically disordered regions than in those encoding structural domains
Codon usage tends to be optimized in highly expressed genes. A plausible explanation for this phenomenon is that translational accuracy is increased in highly expressed genes with infrequent use of rare codons. Besides structural domains (SDs), eukaryotic proteins generally have intrinsically disord...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137448/ https://www.ncbi.nlm.nih.gov/pubmed/27915289 http://dx.doi.org/10.1093/nar/gkw899 |