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The multifaceted influence of histone deacetylases on DNA damage signalling and DNA repair

Histone/protein deacetylases play multiple roles in regulating gene expression and protein activation and stability. Their deregulation during cancer initiation and progression cause resistance to therapy. Here, we review the role of histone deacetylases (HDACs) and the NAD(+) dependent sirtuins (SI...

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Detalles Bibliográficos
Autores principales:	Roos, Wynand Paul, Krumm, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Survey and Summary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137451/ https://www.ncbi.nlm.nih.gov/pubmed/27738139 http://dx.doi.org/10.1093/nar/gkw922

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