Dephosphorylation of the Retinoblastoma protein (Rb) inhibits cancer cell EMT via Zeb

The tumor suppressor Retinoblastoma (Rb) protein is highly phosphorylated in cancer cells largely due to the overexpression of cyclins or the loss of expression of cyclin dependent kinase inhibitors (cdki). Hyperphosphorylation of Rb promotes proliferation, and plays a role in the regulation of apop...

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Detalles Bibliográficos
Autores principales: Egger, Jacklynn V., Lane, Maria V., Antonucci, Lisa A., Dedi, Brixhilda, Krucher, Nancy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137485/
https://www.ncbi.nlm.nih.gov/pubmed/27645778
http://dx.doi.org/10.1080/15384047.2016.1235668

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137485/
https://www.ncbi.nlm.nih.gov/pubmed/27645778
http://dx.doi.org/10.1080/15384047.2016.1235668

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