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A bivalent pneumococcal histidine triad protein D-choline-binding protein A vaccine elicits functional antibodies that passively protect mice from Streptococcus pneumoniae challenge

Vaccines based on conserved pneumococcal proteins are being investigated because serotype coverage by pneumococcal polysaccharide and polysaccharide conjugate vaccines is incomplete and may eventually decrease due to serotype replacement. Here, we examined the functionality of human antibodies induc...

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Detalles Bibliográficos
Autores principales: Ochs, Martina M., Williams, Kimberley, Sheung, Anthony, Lheritier, Philippe, Visan, Lucian, Rouleau, Nicolas, Proust, Emilie, de Montfort, Aymeric, Tang, Mei, Mari, Karine, Hopfer, Robert, Gallichan, Scott, Brookes, Roger H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137517/
https://www.ncbi.nlm.nih.gov/pubmed/27392182
http://dx.doi.org/10.1080/21645515.2016.1202389