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Diabetes negatively affects cortical and striatal GABAergic neurons: an effect that is partially counteracted by exendin-4

Type 2 diabetic (T2D) patients often develop early cognitive and sensorimotor impairments. The pathophysiological mechanisms behind these problems are largely unknown. Recent studies demonstrate that dysfunctional γ-aminobutyric acid (GABAergic) neurons are involved in age-related cognitive decline....

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Detalles Bibliográficos
Autores principales: Larsson, Martin, Lietzau, Grazyna, Nathanson, David, Östenson, Claes-Göran, Mallard, Carina, Johansson, Maria E., Nyström, Thomas, Patrone, Cesare, Darsalia, Vladimer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137538/
https://www.ncbi.nlm.nih.gov/pubmed/27780892
http://dx.doi.org/10.1042/BSR20160437