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Effects of renal impairment on the pharmacokinetics of orally administered deferiprone

AIMS: In light of the growing recognition of renal disease in thalassemia, it is important to understand the impact of renal impairment on the pharmacokinetics of iron chelators. This study evaluated the pharmacokinetics and safety of the iron chelator deferiprone (DFP) in subjects with renal impair...

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Detalles Bibliográficos
Autores principales: Fradette, Caroline, Pichette, Vincent, Sicard, Éric, Stilman, Anne, Jayashankar, Shalini, Tsang, Yu Chung, Spino, Michael, Tricta, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137824/
https://www.ncbi.nlm.nih.gov/pubmed/27276421
http://dx.doi.org/10.1111/bcp.13037