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Effects of renal impairment on the pharmacokinetics of orally administered deferiprone
AIMS: In light of the growing recognition of renal disease in thalassemia, it is important to understand the impact of renal impairment on the pharmacokinetics of iron chelators. This study evaluated the pharmacokinetics and safety of the iron chelator deferiprone (DFP) in subjects with renal impair...
Autores principales: | Fradette, Caroline, Pichette, Vincent, Sicard, Éric, Stilman, Anne, Jayashankar, Shalini, Tsang, Yu Chung, Spino, Michael, Tricta, Fernando |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137824/ https://www.ncbi.nlm.nih.gov/pubmed/27276421 http://dx.doi.org/10.1111/bcp.13037 |
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