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Supramolecular polymer formation by cyclic dinucleotides and intercalators affects dinucleotide enzymatic processing

BACKGROUND: Cyclic dinucleotides form supramolecular aggregates with intercalators, and this property could be utilized in nanotechnology and medicine. METHODS & RESULTS: Atomic force microscopy and electrophoretic mobility shift assays were used to show that cyclic diguanylic acid (c-di-GMP) fo...

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Detalles Bibliográficos
Autores principales: Nakayama, Shizuka, Zhou, Jie, Zheng, Yue, Szmacinski, Henryk, Sintim, Herman O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137846/
https://www.ncbi.nlm.nih.gov/pubmed/28031943
http://dx.doi.org/10.4155/fso.15.93