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Trinucleotide repeats and protein folding and disease: the perspective from studies with the androgen receptor
The androgen receptor (AR), a ligand activated transcription factor plays a number of roles in reproduction, homeostasis and pathogenesis of disease. It has two major polymorphic sequences; a polyglutamine and a polyglycine repeat that determine the length of the protein and influence receptor foldi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Future Science Ltd
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137883/ https://www.ncbi.nlm.nih.gov/pubmed/28031874 http://dx.doi.org/10.4155/fso.15.47 |