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Transcriptomic Analysis of Mouse Cochlear Supporting Cell Maturation Reveals Large-Scale Changes in Notch Responsiveness Prior to the Onset of Hearing

Neonatal mouse cochlear supporting cells have a limited ability to divide and trans-differentiate into hair cells, but this ability declines rapidly in the two weeks after birth. This decline is concomitant with the morphological and functional maturation of the organ of Corti prior to the onset of...

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Detalles Bibliográficos
Autores principales: Maass, Juan C., Gu, Rende, Cai, Tiantian, Wan, Ying-Wooi, Cantellano, Silvia C., Asprer, Joanna S. T., Zhang, Hongyuan, Jen, Hsin-I, Edlund, Renée K., Liu, Zhandong, Groves, Andrew K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137903/
https://www.ncbi.nlm.nih.gov/pubmed/27918591
http://dx.doi.org/10.1371/journal.pone.0167286