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Extracellular embryo genomic DNA and its potential for genotyping applications
BACKGROUND: Preimplantation genetic diagnosis (PGD) currently relies on biopsy of one or few embryo cells. Our aim was to evaluate the embryo extracellular matrices (spent medium and blastocoele fluid) as source of DNA for embryo genotyping. RESULTS/METHODOLOGY: We first evaluated the amplifiability...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Future Science Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137924/ https://www.ncbi.nlm.nih.gov/pubmed/28031914 http://dx.doi.org/10.4155/fso.15.62 |