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Injectable liposomal formulations of opiorphin as a new therapeutic strategy in pain management

BACKGROUND: Conventional and PEGylated liposomes were developed, aimed at improving the pain-killing effect of opiorphin. METHODS: The antinociceptive action of the formulations was investigated on rats (tail-flick test), and compared with that of opiorphin and morphine aqueous solutions (all at 5 m...

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Detalles Bibliográficos
Autores principales: Mennini, Natascia, Mura, Paola, Nativi, Cristina, Richichi, Barbara, Di Cesare Mannelli, Lorenzo, Ghelardini, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137926/
https://www.ncbi.nlm.nih.gov/pubmed/28031877
http://dx.doi.org/10.4155/fso.14.3