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The case of galantamine: repurposing and late blooming of a cholinergic drug
Galantamine is a reversible inhibitor of cholinesterases and an allosteric modulator of neuronal nicotinic acetylcholine receptors which restores reduced cholinergic tone in the central and peripheral nervous system. Characterized in the early 1950s in Bulgaria, it saw limited use for paralytic and...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Future Science Ltd
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137937/ https://www.ncbi.nlm.nih.gov/pubmed/28031923 http://dx.doi.org/10.4155/fso.15.73 |