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The role and therapeutic targeting of α-, β- and γ-secretase in Alzheimer's disease

Alzheimer's disease (AD) is the most common form of dementia in the elderly and its prevalence is set to increase rapidly in coming decades. However, there are as yet no available drugs that can halt or even stabilize disease progression. One of the main pathological features of AD is the prese...

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Detalles Bibliográficos
Autores principales: MacLeod, Ruth, Hillert, Ellin-Kristina, Cameron, Ryan T, Baillie, George S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137966/
https://www.ncbi.nlm.nih.gov/pubmed/28031886
http://dx.doi.org/10.4155/fso.15.9