Loading cisplatin onto 6-mercaptopurine covalently modified MSNS: a nanomedicine strategy to improve the outcome of cisplatin therapy

In the treatment of cancer patients, cisplatin (CDDP) exhibits serious cardiac and renal toxicities, while classical combinations related to CDDP are unable to solve these problems and may result in worse prognosis. Alternately, this study covalently conjugated 6-mercaptopurine (6MP) onto the surfac...

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Detalles Bibliográficos
Autores principales: Lv, Xiaojie, Zhao, Ming, Wang, Yuiji, Hu, Xi, Wu, Jianhui, Jiang, Xueyun, Li, Shan, Cui, Chunying, Peng, Shiqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138022/
https://www.ncbi.nlm.nih.gov/pubmed/27942204
http://dx.doi.org/10.2147/DDDT.S116286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138022/
https://www.ncbi.nlm.nih.gov/pubmed/27942204
http://dx.doi.org/10.2147/DDDT.S116286

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