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Smad4 restricts differentiation to promote expansion of satellite cell derived progenitors during skeletal muscle regeneration
Skeletal muscle regenerative potential declines with age, in part due to deficiencies in resident stem cells (satellite cells, SCs) and derived myogenic progenitors (MPs); however, the factors responsible for this decline remain obscure. TGFβ superfamily signaling is an inhibitor of myogenic differe...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138033/ https://www.ncbi.nlm.nih.gov/pubmed/27855784 http://dx.doi.org/10.7554/eLife.19484 |