Actin is an evolutionarily-conserved damage-associated molecular pattern that signals tissue injury in Drosophila melanogaster

Damage-associated molecular patterns (DAMPs) are molecules released by dead cells that trigger sterile inflammation and, in vertebrates, adaptive immunity. Actin is a DAMP detected in mammals by the receptor, DNGR-1, expressed by dendritic cells (DCs). DNGR-1 is phosphorylated by Src-family kinases...

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Detalles Bibliográficos
Autores principales: Srinivasan, Naren, Gordon, Oliver, Ahrens, Susan, Franz, Anna, Deddouche, Safia, Chakravarty, Probir, Phillips, David, Yunus, Ali A, Rosen, Michael K, Valente, Rita S, Teixeira, Luis, Thompson, Barry, Dionne, Marc S, Wood, Will, Reis e Sousa, Caetano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138034/
https://www.ncbi.nlm.nih.gov/pubmed/27871362
http://dx.doi.org/10.7554/eLife.19662

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138034/
https://www.ncbi.nlm.nih.gov/pubmed/27871362
http://dx.doi.org/10.7554/eLife.19662

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