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CTGF enhances resistance to 5-FU-mediating cell apoptosis through FAK/MEK/ERK signal pathway in colorectal cancer

Colorectal cancer (CRC) is one of the most commonly diagnosed cancers among both males and females; the chemotherapy drug 5-fluorouracil (5-FU) is one of a doctors’ first lines of defense against CRC. However, therapeutic failures are common because of the emergence of drug resistance. Connective ti...

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Detalles Bibliográficos
Autores principales: Yang, Kai, Gao, Kai, Hu, Gui, Wen, Yanguang, Lin, Changwei, Li, Xiaorong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138041/
https://www.ncbi.nlm.nih.gov/pubmed/27942222
http://dx.doi.org/10.2147/OTT.S108929