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Halogenated indoles eradicate bacterial persister cells and biofilms
The emergence of antibiotic resistance has necessitated new therapeutic approaches to combat recalcitrant bacterial infections. Persister cells, often found in biofilms, are metabolically dormant, and thus, are highly tolerant to all traditional antibiotics and represent a major drug resistance mech...
Autores principales: | Lee, Jin-Hyung, Kim, Yong-Guy, Gwon, Giyeon, Wood, Thomas K., Lee, Jintae |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138170/ https://www.ncbi.nlm.nih.gov/pubmed/27921270 http://dx.doi.org/10.1186/s13568-016-0297-6 |
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