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Myocardial Contractile Dysfunction Is Present without Histopathology in a Mouse Model of Limb-Girdle Muscular Dystrophy-2F and Is Prevented after Claudin-5 Virotherapy

Mutations in several members of the dystrophin glycoprotein complex lead to skeletal and cardiomyopathies. Cardiac care for these muscular dystrophies consists of management of symptoms with standard heart medications after detection of reduced whole heart function. Recent evidence from both Duchenn...

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Detalles Bibliográficos
Autores principales: Milani-Nejad, Nima, Schultz, Eric J., Slabaugh, Jessica L., Janssen, Paul M. L., Rafael-Fortney, Jill A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138189/
https://www.ncbi.nlm.nih.gov/pubmed/27999547
http://dx.doi.org/10.3389/fphys.2016.00539