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A Previous Miscarriage and a Previous Successful Pregnancy Have a Different Impact on HLA Antibody Formation during a Subsequent Successful Pregnancy

Inherited paternal HLA antigens from the semi-allogeneic fetus may trigger maternal immune responses during pregnancy, leading to the production of child-specific HLA antibodies. The prevalence of these HLA antibodies increases with the number of successful pregnancies. In the present study, we inve...

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Detalles Bibliográficos
Autores principales: Geneugelijk, Kirsten, Hönger, Gideon, van Deutekom, Hanneke Wilhelmina Maria, Hösli, Irene Mathilde, Schaub, Stefan, Spierings, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138233/
https://www.ncbi.nlm.nih.gov/pubmed/27999574
http://dx.doi.org/10.3389/fimmu.2016.00571