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Activation of the Ca(2+)-sensing receptors increases currents through inward rectifier K(+) channels via activation of phosphatidylinositol 4-kinase
Inward rectifier K(+) channels are important for maintaining normal electrical function in many cell types. The proper function of these channels requires the presence of membrane phosphoinositide 4,5-bisphosphate (PIP(2)). Stimulation of the Ca(2+)-sensing receptor CaR, a pleiotropic G protein-coup...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138266/ https://www.ncbi.nlm.nih.gov/pubmed/27838849 http://dx.doi.org/10.1007/s00424-016-1901-y |