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Activation of the Ca(2+)-sensing receptors increases currents through inward rectifier K(+) channels via activation of phosphatidylinositol 4-kinase

Inward rectifier K(+) channels are important for maintaining normal electrical function in many cell types. The proper function of these channels requires the presence of membrane phosphoinositide 4,5-bisphosphate (PIP(2)). Stimulation of the Ca(2+)-sensing receptor CaR, a pleiotropic G protein-coup...

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Detalles Bibliográficos
Autores principales: Liu, Chung-Hung, Chang, Hsueh-Kai, Lee, Sue-Ping, Shieh, Ru-Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138266/
https://www.ncbi.nlm.nih.gov/pubmed/27838849
http://dx.doi.org/10.1007/s00424-016-1901-y