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Identification of critical paralog groups with indispensable roles in the regulation of signaling flow

Extensive cross-talk between signaling pathways is required to integrate the myriad of extracellular signal combinations at the cellular level. Gene duplication events may lead to the emergence of novel functions, leaving groups of similar genes - termed paralogs - in the genome. To distinguish crit...

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Detalles Bibliográficos
Autores principales: Modos, Dezso, Brooks, Johanne, Fazekas, David, Ari, Eszter, Vellai, Tibor, Csermely, Peter, Korcsmaros, Tamas, Lenti, Katalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138592/
https://www.ncbi.nlm.nih.gov/pubmed/27922122
http://dx.doi.org/10.1038/srep38588