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New arylated benzo[h]quinolines induce anti-cancer activity by oxidative stress-mediated DNA damage

The anti-cancer activity of the benzo[h]quinolines was evaluated on cultured human skin cancer (G361), lung cancer (H460), breast cancer (MCF7) and colon cancer (HCT116) cell lines. The inhibitory effect of these compounds on the cell growth was determined by the MTT assay. The compounds 3e, 3f, 3h...

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Detalles Bibliográficos
Autores principales: Yadav, Dharmendra K., Rai, Reeta, Kumar, Naresh, Singh, Surjeet, Misra, Sanjeev, Sharma, Praveen, Shaw, Priyanka, Pérez-Sánchez, Horacio, Mancera, Ricardo L., Choi, Eun Ha, Kim, Mi-hyun, Pratap, Ramendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138627/
https://www.ncbi.nlm.nih.gov/pubmed/27922047
http://dx.doi.org/10.1038/srep38128