Identification and Structural Characterization of the N-terminal Amyloid Core of Orb2 isoform A

Orb2 is a functional amyloid that plays a key role in Drosophila long-term memory formation. Orb2 has two isoforms that differ in their N-termini. The N-terminus of the A isoform (Orb2A) that precedes its Q-rich prion-like domain has been shown to be important for Orb2 aggregation and long-term memo...

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Detalles Bibliográficos
Autores principales: Cervantes, Silvia A., Bajakian, Thalia H., Soria, Maria A., Falk, Alexander S., Service, Rachel J., Langen, Ralf, Siemer, Ansgar B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138630/
https://www.ncbi.nlm.nih.gov/pubmed/27922050
http://dx.doi.org/10.1038/srep38265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138630/
https://www.ncbi.nlm.nih.gov/pubmed/27922050
http://dx.doi.org/10.1038/srep38265

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