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Function and regulation of tau conformations in the development and treatment of traumatic brain injury and neurodegeneration

One of the two common hallmark lesions of Alzheimer’s disease (AD) brains is neurofibrillary tangles (NFTs), which are composed of hyperphosphorylated tau protein (p-tau). NFTs are also a defining feature of other neurodegenerative disorders and have recently been identified in the brains of patient...

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Detalles Bibliográficos
Autores principales: Albayram, Onder, Herbert, Megan K., Kondo, Asami, Tsai, Cheng-Yu, Baxley, Sean, Lian, Xiaolan, Hansen, Madison, Zhou, Xiao Zhen, Lu, Kun Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5139118/
https://www.ncbi.nlm.nih.gov/pubmed/27980715
http://dx.doi.org/10.1186/s13578-016-0124-4