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Effects of Benzo(e)pyrene on Reactive Oxygen/Nitrogen Species and Inflammatory Cytokines Induction in Human RPE Cells and Attenuation by Mitochondrial-involved Mechanism

PURPOSE: To identify inhibitors that could effectively lower reactive oxygen/nitrogen species (ROS/RNS), complement and inflammatory cytokine levels induced by Benzo(e)pyrene [B(e)p], an element of cigarette smoke, in human retinal pigment epithelial cells (ARPE-19) in vitro. METHODS: ARPE-19 cells...

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Detalles Bibliográficos
Autores principales: Estrago-Franco, M. Fernanda, Moustafa, M. Tarek, Riazi-Esfahani, Mohammad, Sapkal, Ashish U., Piche-Lopez, Rhina, Patil, A. Jayaprakash, Sharma, Ashish, Falatoonzadeh, Payam, Chwa, Marilyn, Luczy-Bachman, Georgia, Kuppermann, Baruch D., Kenney, M. Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5139551/
https://www.ncbi.nlm.nih.gov/pubmed/27994808
http://dx.doi.org/10.4103/2008-322X.194091