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Effects of Benzo(e)pyrene on Reactive Oxygen/Nitrogen Species and Inflammatory Cytokines Induction in Human RPE Cells and Attenuation by Mitochondrial-involved Mechanism
PURPOSE: To identify inhibitors that could effectively lower reactive oxygen/nitrogen species (ROS/RNS), complement and inflammatory cytokine levels induced by Benzo(e)pyrene [B(e)p], an element of cigarette smoke, in human retinal pigment epithelial cells (ARPE-19) in vitro. METHODS: ARPE-19 cells...
Autores principales: | Estrago-Franco, M. Fernanda, Moustafa, M. Tarek, Riazi-Esfahani, Mohammad, Sapkal, Ashish U., Piche-Lopez, Rhina, Patil, A. Jayaprakash, Sharma, Ashish, Falatoonzadeh, Payam, Chwa, Marilyn, Luczy-Bachman, Georgia, Kuppermann, Baruch D., Kenney, M. Cristina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5139551/ https://www.ncbi.nlm.nih.gov/pubmed/27994808 http://dx.doi.org/10.4103/2008-322X.194091 |
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