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Safety and Immunogenicity of a Candidate Bioconjugate Vaccine against Shigella flexneri 2a Administered to Healthy Adults: a Single-Blind, Randomized Phase I Study

Several candidate vaccines against Shigella spp. are in development, but the lack of a clear correlate of protection from challenge with the induction of adequate immune responses among the youngest age groups in the developing world has hampered Shigella vaccine development over the past several de...

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Detalles Bibliográficos
Autores principales: Riddle, Mark S., Kaminski, Robert W., Di Paolo, Claudio, Porter, Chad K., Gutierrez, Ramiro L., Clarkson, Kristen A., Weerts, Hailey E., Duplessis, Christopher, Castellano, Amy, Alaimo, Cristina, Paolino, Kristopher, Gormley, Robert, Gambillara Fonck, Veronica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5139601/
https://www.ncbi.nlm.nih.gov/pubmed/27581434
http://dx.doi.org/10.1128/CVI.00224-16