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Safety and Immunogenicity of a Candidate Bioconjugate Vaccine against Shigella flexneri 2a Administered to Healthy Adults: a Single-Blind, Randomized Phase I Study
Several candidate vaccines against Shigella spp. are in development, but the lack of a clear correlate of protection from challenge with the induction of adequate immune responses among the youngest age groups in the developing world has hampered Shigella vaccine development over the past several de...
Autores principales: | Riddle, Mark S., Kaminski, Robert W., Di Paolo, Claudio, Porter, Chad K., Gutierrez, Ramiro L., Clarkson, Kristen A., Weerts, Hailey E., Duplessis, Christopher, Castellano, Amy, Alaimo, Cristina, Paolino, Kristopher, Gormley, Robert, Gambillara Fonck, Veronica |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5139601/ https://www.ncbi.nlm.nih.gov/pubmed/27581434 http://dx.doi.org/10.1128/CVI.00224-16 |
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