Dataset of eye disease-related proteins analyzed using the unfolding mutation screen

A number of genetic diseases are a result of missense mutations in protein structure. These mutations can lead to severe protein destabilization and misfolding. The unfolding mutation screen (UMS) is a computational method that calculates unfolding propensities for every possible missense mutation i...

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Detalles Bibliográficos
Autores principales: McCafferty, Caitlyn L., Sergeev, Yuri V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Data Descriptor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5139671/
https://www.ncbi.nlm.nih.gov/pubmed/27922631
http://dx.doi.org/10.1038/sdata.2016.112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5139671/
https://www.ncbi.nlm.nih.gov/pubmed/27922631
http://dx.doi.org/10.1038/sdata.2016.112

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