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Dataset of eye disease-related proteins analyzed using the unfolding mutation screen
A number of genetic diseases are a result of missense mutations in protein structure. These mutations can lead to severe protein destabilization and misfolding. The unfolding mutation screen (UMS) is a computational method that calculates unfolding propensities for every possible missense mutation i...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5139671/ https://www.ncbi.nlm.nih.gov/pubmed/27922631 http://dx.doi.org/10.1038/sdata.2016.112 |