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Control of Gene Expression by RNA Binding Protein Action on Alternative Translation Initiation Sites

Transcript levels do not faithfully predict protein levels, due to post-transcriptional regulation of gene expression mediated by RNA binding proteins (RBPs) and non-coding RNAs. We developed a multivariate linear regression model integrating RBP levels and predicted RBP-mRNA regulatory interactions...

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Detalles Bibliográficos
Autores principales: Re, Angela, Waldron, Levi, Quattrone, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5140048/
https://www.ncbi.nlm.nih.gov/pubmed/27923063
http://dx.doi.org/10.1371/journal.pcbi.1005198