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Sparse Regression Based Structure Learning of Stochastic Reaction Networks from Single Cell Snapshot Time Series

Stochastic chemical reaction networks constitute a model class to quantitatively describe dynamics and cell-to-cell variability in biological systems. The topology of these networks typically is only partially characterized due to experimental limitations. Current approaches for refining network top...

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Detalles Bibliográficos
Autores principales: Klimovskaia, Anna, Ganscha, Stefan, Claassen, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5140059/
https://www.ncbi.nlm.nih.gov/pubmed/27923064
http://dx.doi.org/10.1371/journal.pcbi.1005234