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Comparative Transcriptomic and Epigenomic Analyses Reveal New Regulators of Murine Brown Adipogenesis

Increasing energy expenditure through brown adipocyte recruitment is a promising approach to combat obesity. We report here the comprehensive profiling of the epigenome and transcriptome throughout the lineage commitment and differentiation of C3H10T1/2 mesenchymal stem cell line into brown adipocyt...

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Detalles Bibliográficos
Autores principales: Brunmeir, Reinhard, Wu, Jingyi, Peng, Xu, Kim, Sun-Yee, Julien, Sofi G., Zhang, Qiongyi, Xie, Wei, Xu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5140063/
https://www.ncbi.nlm.nih.gov/pubmed/27923061
http://dx.doi.org/10.1371/journal.pgen.1006474