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Crystal Structure of the Salmonella Typhimurium Effector GtgE

Salmonella Typhimurium GtgE is an effector protein contributing to the virulence of this pathogen. It was shown to possess highly selective proteolytic activity against a subset of Rab proteins that helps in evasion of Salmonella-containing vacuole (SCV) fusion with lysosomes. Cys45, His151 and Asp1...

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Detalles Bibliográficos
Autores principales: Xu, Caishuang, Kozlov, Guennadi, Wong, Kathy, Gehring, Kalle, Cygler, Miroslaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5140068/
https://www.ncbi.nlm.nih.gov/pubmed/27923041
http://dx.doi.org/10.1371/journal.pone.0166643