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The structure of SV40 large T hexameric helicase in complex with AT-rich origin DNA

DNA replication is a fundamental biological process. The initial step in eukaryotic DNA replication is the assembly of the pre-initiation complex, including the formation of two head-to-head hexameric helicases around the replication origin. How these hexameric helicases interact with their origin d...

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Detalles Bibliográficos
Autores principales: Gai, Dahai, Wang, Damian, Li, Shu-Xing, Chen, Xiaojiang S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5140265/
https://www.ncbi.nlm.nih.gov/pubmed/27921994
http://dx.doi.org/10.7554/eLife.18129