Identification of CASZ1 nuclear export signal (NES) reveals potential mechanisms for loss of CASZ1 tumor suppressor activity in neuroblastoma

As a transcription factor, localization to the nucleus and the recruitment of co-factors to regulate gene transcription is essential. Nuclear localization and nucleosome remodeling and histone deacetylase (NuRD) complex binding are required for the zinc finger transcription factor CASZ1 to function...

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Detalles Bibliográficos
Autores principales: Liu, Zhihui, Lam, Norris, Wang, Evelyn, Virden, Ryan A., Pawel, Bruce, Attiyeh, Edward F., Maris, John M., Thiele, Carol J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5140774/
https://www.ncbi.nlm.nih.gov/pubmed/27270431
http://dx.doi.org/10.1038/onc.2016.179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5140774/
https://www.ncbi.nlm.nih.gov/pubmed/27270431
http://dx.doi.org/10.1038/onc.2016.179

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