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Identification of CASZ1 nuclear export signal (NES) reveals potential mechanisms for loss of CASZ1 tumor suppressor activity in neuroblastoma

As a transcription factor, localization to the nucleus and the recruitment of co-factors to regulate gene transcription is essential. Nuclear localization and nucleosome remodeling and histone deacetylase (NuRD) complex binding are required for the zinc finger transcription factor CASZ1 to function...

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Detalles Bibliográficos
Autores principales:	Liu, Zhihui, Lam, Norris, Wang, Evelyn, Virden, Ryan A., Pawel, Bruce, Attiyeh, Edward F., Maris, John M., Thiele, Carol J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5140774/ https://www.ncbi.nlm.nih.gov/pubmed/27270431 http://dx.doi.org/10.1038/onc.2016.179

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